Not really.
But if I comprehend your intent correctly, always prioritise pure click/idle multiplier perks then ymen multiplier perks.
After those are the x per y click and so, followed by HC/KH/CH click/idle multipliers. Then everything else (-price, +mojo on reset etc.).
HOWEVER, getting perks such as Angela's 3rd perk (+10% affecion per click) take precedence over all as they allow you to max girls faster.